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Measure developers use the C-statistic to assess risk-adjusted models, it indicates the ability of the model to discriminate between one event and the other. If a model discriminates randomly, c = 0.5. If the risk factor modeling predicts the outcome well, then discrimination increases. The higher the c-statistic, the better the predictive power of the model.

Calculation Algorithm
A calculation algorithm is an ordered sequence of data element retrieval and aggregation through which numerator and denominator events or continuous variable values are identified by a measure. Also referred to as the performance calculation.

Clinical Practice Guidelines
Clinical practice guidelines are systematically developed statements to support practitioner and patient decisions about appropriate healthcare for specific clinical circumstances.

Clinical Quality Language (CQL)
CQL is a Health Level Seven International® (HL7®) Standard for Trial Use. It is part of the effort to harmonize standards between electronic clinical quality measures (eCQMs) and clinical decision support. CQL provides the ability to express logic that is human-readable yet structured enough for processing a query electronically. It replaces the logic expressions previously defined in the Quality Data Model (QDM) and QDM for use with CQL includes only the method for defining the data elements (i.e., data model).

Clinical Quality Measure (CQM)
A clinical quality measure is a mechanism used for assessing the degree to which a provider competently and safely delivers clinical services that are appropriate for the patient in an optimal time frame. CQMs are a subset of the broader category of performance measures.

Code Language
A code language, also known as programming language, is a set of commands, instructions, and other syntax used to create a software program. A high-level language is what a programmer uses to write code. The programmer compiles the code into a low-level language, which computer hardware recognizes directly (Christensson, 2011).

Code System
A code system is a managed collection of concepts with each concept represented by at least one internally unique code and a human-readable description (e.g., SNOMED CT).

Collinearity is when two or more variables are exactly correlated which means the regression coefficients are not uniquely determined. Collinearity hurts the interpretability of the model because the regression coefficients are not unique and have influences from other features (Saslow, n.d.).

Competing Measures
Competing measures address the same topic and the same population. Use this term  when considering harmonization. Refer to Related Measures.

Composite Measure
A composite measure is a measure that contains two or more individual measures, resulting in a single measure with a single score.

Conceptual Framework
A conceptual framework is a theoretical structure of assumptions, principles, and rules that holds together the ideas comprising a broad concept.

Conflict of Interest
A conflict of interest exists when an individual (or entity) has more than one motivation for trying to achieve an objective. In measure development, this situation arises when an individual has opportunities to affect specifications for quality measures that impact an interest with which the individual has a relationship.

Construct Validity
Construct validity is the extent to which the measure actually measures what it claims to measure. Construct validity evidence often involves empirical and theoretical support for the interpretation of the construct.

Continuous Variable (CV)
A continuous variable is a measure score in which each individual value for the measure can fall anywhere along a continuous scale and can be aggregated using a variety of methods such as the calculation of a mean or median (e.g., mean number of minutes between presentation of chest pain to the time of administration of thrombolytics).

Convergent Validity (concurrent validity)
Convergent validity refers to the degree to which multiple measures of a single concept are correlated.

Cost of Care
The cost of care is the total healthcare spending, including total resource use and unit price, by payer or consumer, for a healthcare service or group of healthcare services associated with a specified patient population, time period, and unit of clinical accountability.

Cost/Resource Use Measure
A cost/resource use measure is a measure of health services counts (in terms of units or dollars) applied to a population or event (including diagnoses, procedures, or encounters). A resource use measure counts the frequency of use of defined health system resources. Some may further apply a dollar amount (e.g., allowable charges, paid amounts, or standardized prices) to each unit of resource use.

A criterion is an accepted standard, principle, or rule used to make a decision or to inform an evaluator’s judgment.

Criterion Validity
Criterion validity measures how well one measure predicts the outcome for another measure or verifies data elements against some reference criterion determined to be valid (i.e., the gold standard).

Critical Data Element
A critical data element is an element that contributes most to the computed measure score, that is, account for identifying the greatest proportion of the target condition, event, or outcome being measured (numerator); the target population (denominator); population excluded (exclusion); and when applicable, risk factors with largest contribution to variability in outcome.